OSOPIA® – The world's first
synthetically fabricated
bone graft with
3DI Surface Technology

Osopia

OSOPIA® is a synthetic Biphasic Calcium Phosphate (BCP) manufactured using an innovative proprietary process with 3DI Surface Technology. Read more here.

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OSOPIA BENEFITS:

SUSTAINED REGENERATION

Slow resorption profile providing continuous remodeling process for 100% vital bone.

FULLY SYNTHETIC

Synthetic graft concept designed for maximum product safety and performance.

INDICATIONS:​

OsOpia is a bone grafting material indicated for use in the specific
treatment of extraction sockets and maxillary sinus augmentation procedures.

Osopia 0.5cc

Osopia 0.5cc

Osopia 1cc

Osopia 1cc

Osopia 2cc

Osopia 2cc

Research References

Miron RJ, Sculean A, Shuang Y, Bosshardt DD, Gruber R, Buser D, Chandad F, Zhang Y. Osteoinductive potential of a novel biphasic calcium phosphate bone graft in comparison with autographs, xenografts, and DFDBA. Clin Oral Implants Res. 2016 Jun;27(6):668-75. doi: 10.1111/clr.12647. (IF = 3.624)

 

Miron RJ, Shuang Y, Bosshardt DD, Caballé-Serrano J, Chandad F,Zhang Y. Osteogenic gene array of osteoblasts cultured on a novel osteoinductive biphasic calcium phosphate bone grafting material. Clin Oral Investig. 2017 Apr;21(3):801-808. doi: 10.1007/s00784-016-1825-0. Epub 2016 Apr 23. (IF = 2.308)

 

Miron RJ, Zhang Q, Sculean A, Buser D, Pippenger BE, Dard M, Shirakata Y, Chandad F, Zhang Y. Osteoinductive potential of 4 commonly employed bone grafts. Clin Oral Investig. 2016 Nov;20(8):2259-2265. (IF = 2.308)

 

Zhang Y, Shuang Y, Zhou W, Fu H, Qian L, Miron RJ. Addition of a synthetically fabricated osteoinductive biphasic calcium phosphate bone graft to BMP2 improves new bone formation. Clin Implant Dent Relat Res. 2016 Dec;18(6):1238-1247. doi: 10.1111/cid.12384. Epub 2015 Oct 28. (IF = 2.939)

 

Miron RJ, Zhang Y. The Arrival of Synthetic Bone Grafts with Osteoinductive Potential. J J Dent Res. 2014, 1(1): 002.

 

Barroso-Panella A, Gargallo-Albiol J, Hérnandez-Alfaro F Evaluation of Bone Stability and Esthetic Results After Immediate Implant Placement Using a Novel Synthetic Bone Substitute in the Anterior Zone: Results After 12 Months. Int J Periodontics Restorative Dent. 2018 Mar/Apr;38(2):235-243. doi: 10.11607/prd.2863.

Osopia Publications

Yuan H, et al. (2010) Osteoinductive ceramics as a synthetic alternative to autologous bone grafting.

 

Klijn RJ, et al. (2011) Maxillary sinus augmentation with microstructured  tricalcium phosphate ceramic in sheep.

 

Song G, et al. (2013) The homing of bone marrow MSCs to non-osseous sites for ectopic bone formation induced by osteoinductive calcium phosphate.

 

de Ruiter A, et al. (2014) Micro-structured calcium phosphate ceramic for donor site repair after harvesting chin bone for grafting alveolar clefts in children.

 

Dahlin C, et al. (2015) Bone tissue modelling and remodelling following guided bone regeneration in combination with biphasic calcium phosphate materials presenting different microporosity.

 

Yip I, et al. (2015) Defect healing with various bone substitutes.

 

Sharif F, et al. (2016) Dental materials for cleft palate repair.

 

Kitayama S, et al. (2016) Regeneration of rabbit calvarial defects using biphasic calcium phosphate and a strontium hydroxyapatite-containing collagen membrane.

 

Zhang Q, et al. (2018) Histomorphometric Study of New Bone Formation Comparing Defect Healing with Three Bone Grafting Materials: The Effect of Osteoporosis on Graft Consolidation

Disclaimer
  • In vitro or in vivo studies may not be predictive of clinical experience in humans.
  • OsOpia is not cleared by FDA as an osteoinductive bone graft.